Using a technique called spatial transcriptomics, we have analysed the gene expression in the mouse colon and created a map showing where in the tissue individual genes are expressed. The study is published in the journal Nature Communications.
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Published: 2022-02-11
Using zebrafish and mouse we showed that Gpr35 transcripts are modulated by the microbiota as well as chemically and infection-induced intestinal inflammation. Using genetic knockouts for GPR35 both in vivo and at the cellular level, we identify a role for GPR35 in triggering.
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Published: 2021-09-06
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Published: 2020-04-13
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Published: 2019-12-11
Using longitudinal colon gene expression analysis from the acute epithelial injury and recovery phases of DSS colitis in mice, we have informed the molecular classification of Ulcerative Colitis (UC) patients. This study was published in Nature Communications.
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Published: 2019-06-28
Villablanca Lab | KI 