Qianzhou YU
Postdoctoral fellow
The intestine is essential for absorbing life-sustaining nutrients while defending the host against external pathogens and toxins. However, how the intestine transmits nutritional signals to the immune system and adapts to dietary intake remains largely unknown. During my PhD, I uncovered a previously unrecognized role of Gasdermin D, a molecule classically associated with pyroptosis, in lipid absorption and in supporting the maintenance of intestinal γδ intraepithelial lymphocytes. Currently, as a postdoctoral researcher in the Villablanca lab, my research focuses on the interplay between diet and intestinal immunity, including how dietary cues shape local immune responses and how immune cells, in turn, facilitate fundamental intestinal functions, e.g., wound healing and nutrient absorption.
Villablanca Lab | KI 